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Shanthi V Sitaraman Selected Research

Dextrans (Dextran)

5/2013Constitutive expression of MMP9 in intestinal epithelium worsens murine acute colitis and is associated with increased levels of proinflammatory cytokine Kc.
10/2012A(₂B)AR expression in non-immune cells plays an important role in the development of murine colitis.
1/2012Dextran sodium sulfate (DSS) induces colitis in mice by forming nano-lipocomplexes with medium-chain-length fatty acids in the colon.
10/2011The PepT1-NOD2 signaling pathway aggravates induced colitis in mice.
5/2011Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis.
3/2010Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model.
1/2010Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer.
7/2009Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice.
6/2009Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis.
2/2009Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis.
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Shanthi V Sitaraman Research Topics

Disease

35Inflammation (Inflammations)
11/2013 - 09/2002
25Colitis
11/2013 - 12/2005
17Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
10/2011 - 09/2002
3Insulin Resistance
03/2014 - 03/2008
3Neoplasms (Cancer)
10/2011 - 10/2006
3Ulcerative Colitis
01/2011 - 06/2005
3Crohn Disease (Crohn's Disease)
11/2008 - 11/2003
3Short Bowel Syndrome
02/2008 - 11/2006
2Colitis-Associated Neoplasms
10/2011 - 01/2010
2Body Weight (Weight, Body)
05/2011 - 07/2007
2Carcinoma (Carcinomatosis)
05/2011 - 10/2006
2Hyperglycemia
03/2008 - 02/2006
2Ischemia
02/2006 - 02/2006
2Rheumatoid Arthritis
09/2003 - 09/2002
1Obesity
03/2014
1Weight Gain
03/2014
1Weight Loss (Weight Reduction)
05/2013
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2011
1Pathologic Neovascularization
01/2011
1Necrosis
11/2010
1Hypertension (High Blood Pressure)
04/2010
1Hyperphagia (Overeating)
04/2010
1Hyperlipidemias (Hyperlipidemia)
04/2010
1Infections
04/2010
1Metabolic Syndrome (Dysmetabolic Syndrome X)
04/2010
1Colonic Neoplasms (Colon Cancer)
01/2010
1Carcinogenesis
01/2010

Drug/Important Bio-Agent (IBA)

16Dextrans (Dextran)FDA Link
05/2013 - 12/2005
14CytokinesIBA
11/2013 - 09/2003
14sodium sulfate (sodium bisulfate)FDA LinkGeneric
05/2013 - 12/2005
9Proteins (Proteins, Gene)FDA Link
06/2012 - 09/2004
7Matrix Metalloproteinases (MMPs)IBA
10/2011 - 12/2005
6Adenosine (Adenocard)FDA LinkGeneric
06/2010 - 09/2002
5Messenger RNA (mRNA)IBA
05/2013 - 09/2008
5Peroxidase (Myeloperoxidase)IBA
05/2011 - 09/2006
5Fibronectins (Fibronectin)IBA
11/2007 - 09/2004
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2013 - 10/2008
4Sulfonic AcidsIBA
10/2011 - 09/2008
4Phosphotransferases (Kinase)IBA
08/2011 - 10/2006
4ProhibitinsIBA
05/2011 - 01/2007
4NF-kappa B (NF-kB)IBA
05/2011 - 09/2003
4Interleukin-6 (Interleukin 6)IBA
07/2006 - 09/2003
3Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
03/2014 - 02/2006
3Glycoproteins (Glycoprotein)IBA
06/2012 - 10/2006
3Matrix Metalloproteinase 9 (Gelatinase B)IBA
10/2011 - 10/2006
3Proline (L-Proline)FDA Link
08/2011 - 10/2008
3Dextran SulfateIBA
08/2011 - 06/2009
3Alanine (L-Alanine)FDA Link
08/2011 - 10/2008
3ChloridesIBA
01/2009 - 11/2004
3FlagellinIBA
02/2008 - 11/2004
2Glial Fibrillary Acidic ProteinIBA
03/2014 - 02/2006
2Neuropeptide YIBA
11/2013 - 10/2008
2SodiumIBA
10/2012 - 10/2008
2MicroRNAs (MicroRNA)IBA
06/2012 - 01/2010
2Glucose (Dextrose)FDA LinkGeneric
01/2012 - 02/2006
2Pharmaceutical PreparationsIBA
01/2012 - 03/2010
2HydrogelsIBA
01/2012 - 03/2010
2Insulin (Novolin)FDA Link
10/2011 - 03/2008
2sym-trinitrobenzeneIBA
10/2011 - 09/2008
2NucleotidesIBA
10/2011 - 02/2008
2AntioxidantsIBA
05/2011 - 07/2009
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
02/2009 - 09/2006
2ChemokinesIBA
10/2008 - 07/2007
2Immunoglobulins (Immunoglobulin)IBA
02/2008 - 02/2005
2NucleosidesIBA
02/2008 - 02/2006
2Toll-Like Receptors (Toll-Like Receptor)IBA
07/2007 - 02/2005
2Peptide Hydrolases (Proteases)FDA Link
01/2007 - 12/2005
2GelatinasesIBA
09/2006 - 12/2005
1XENP 1595IBA
11/2013
1Etanercept (Enbrel)FDA Link
11/2013
1Tumor Necrosis Factor InhibitorsIBA
11/2013
1SolutionsIBA
01/2012
1Fatty Acids (Saturated Fatty Acids)IBA
01/2012
1Biocompatible Materials (Biomaterials)IBA
01/2012
1Anti-Bacterial Agents (Antibiotics)IBA
10/2011
1Transcription Factors (Transcription Factor)IBA
10/2011
1villinIBA
10/2011
12'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA
10/2011
1OligonucleotidesIBA
10/2011
1poly(lactide) (polylactic acid)IBA
05/2011
1Drinking WaterIBA
02/2011
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
01/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2011
1EndostatinsIBA
01/2011
1Small Interfering RNA (siRNA)IBA
11/2010
1L-Ala-gamma-D-Glu-meso-diaminopimelic acidIBA
09/2010
1Toll-Like Receptor 5IBA
04/2010
1Polysaccharides (Glycans)IBA
03/2010
1MSH (11-13)IBA
03/2010
1beta CateninIBA
01/2010
1AzoxymethaneIBA
01/2010
1DNA (Deoxyribonucleic Acid)IBA
07/2009
1Free RadicalsIBA
07/2009
1Nuclear Proteins (Protein, Nuclear)IBA
07/2009
1Indicators and Reagents (Reagents)IBA
06/2009
1GadoliniumIBA
11/2008
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
10/2008

Therapy/Procedure

2Oral Administration
05/2011 - 07/2007
1Enema (Enemas)
05/2011
1Therapeutics
06/2009